Follow-up study on ThinPrep cytology test-positive patients in tropical regions

Autor: Yun-Chun, Chen, Chong-Nan, Liang, Xiang-Feng, Wang, Min-Fa, Wang, Xu-Ning, Huang, Jian-Dong, Hu
Rok vydání: 2022
Předmět:
Zdroj: World Journal of Clinical Cases. 10:12543-12550
ISSN: 2307-8960
DOI: 10.12998/wjcc.v10.i34.12543
Popis: As shown in the statistics from the World Health Organization, it is estimated that approximately 75000 new cases of cervical cancer occur every year in China. In 2008, 33000 people died of cervical cancer in China. It is proven that most women are at risk of cervical cancer. The progression from human papillomavirus (HPV) infection to cervical cancer can be several years or decades, which offers a unique opportunity to prevent cancer.To observe the changes in ThinPrep cytology tests (TCT) and HPV infection in patients who were detected to be positiveThis paper performed a follow-up study on 206 cervical cancer screening-positive patients of 12231 total cases from our previous research. We conducted an observational study on the TCT results based on the interpretation of The Bethesda System.Over a 5-year period, 10 cases received consistent follow-up. The proportions of cases in which glandular epithelial lesions were detected increased over the follow-up period. The differences between the years were statistically significant (The follow-up study for 5 years to 9 years revealed a tendency to change from squamous epithelial lesions to glandular epithelial lesions and an improvement of the disease (which had not been reported previously). The HPV test indicated a high negative conversion ratio of the viral infection. However, the follow-up cases were not found to have persistent infection of high-risk HPV. Therefore, early intervention of cervical cancer screening is necessary. Low re-examination compliance, patient education, and preventive measures should be enhanced.
Databáze: OpenAIRE