Nutrition in Necrotizing Enterocolitis and Following Intestinal Resection

Autor: Cathleen M. Courtney, Brad W. Warner, Allie E. Steinberger, Jocelyn Ou, Maria E. Tecos
Jazyk: angličtina
Rok vydání: 2020
Předmět:
0301 basic medicine
intestinal resection
medicine.medical_specialty
Parenteral Nutrition
microbiome
lcsh:TX341-641
Review
intestinal adaptation
Breast milk
short bowel syndrome
law.invention
03 medical and health sciences
0302 clinical medicine
Randomized controlled trial
law
Enterocolitis
Necrotizing
medicine
Animals
Humans
030212 general & internal medicine
Intensive care medicine
Infant Nutritional Physiological Phenomena
030109 nutrition & dietetics
Nutrition and Dietetics
necrotizing enterocolitis
Medical treatment
hormones
Milk
Human
business.industry
prematurity
Infant
Newborn
Infant
Short bowel syndrome
medicine.disease
Additional research
digestive system diseases
Infant Formula
3. Good health
Intestines
Parenteral nutrition
Milk
Necrotizing enterocolitis
breast milk
Intestinal resection
business
lcsh:Nutrition. Foods and food supply
Infant
Premature
Food Science
Zdroj: Nutrients
Nutrients, Vol 12, Iss 2, p 520 (2020)
ISSN: 2072-6643
Popis: This review aims to discuss the role of nutrition and feeding practices in necrotizing enterocolitis (NEC), NEC prevention, and its complications, including surgical treatment. A thorough PubMed search was performed with a focus on meta-analyses and randomized controlled trials when available. There are several variables in nutrition and the feeding of preterm infants with the intention of preventing necrotizing enterocolitis (NEC). Starting feeds later rather than earlier, advancing feeds slowly and continuous feeds have not been shown to prevent NEC and breast milk remains the only effective prevention strategy. The lack of medical treatment options for NEC often leads to disease progression requiring surgical resection. Following resection, intestinal adaptation occurs, during which villi lengthen and crypts deepen to increase the functional capacity of remaining bowel. The effect of macronutrients on intestinal adaptation has been extensively studied in animal models. Clinically, the length and portion of intestine that is resected may lead to patients requiring parenteral nutrition, which is also reviewed here. There remain significant gaps in knowledge surrounding many of the nutritional aspects of NEC and more research is needed to determine optimal feeding approaches to prevent NEC, particularly in infants younger than 28 weeks and
Databáze: OpenAIRE
Externí odkaz: