Effect of Camphylobacter rectus on Serum Iron and Transferrin- Invivo Findings
| Autor: | Pradnya Prabhakar Mali, Dattatray Anant Darawade, Suresh Vasant Lele, Manjushri Raghavendra Medikeri, Pinal Mahendra Jain, Raghavendra Shrishail Medikeri |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
chemistry.chemical_classification
Periodontitis medicine.diagnostic_test business.industry microbiology/polymerase chain reaction Clinical Biochemistry lcsh:R Physiology lcsh:Medicine chronic periodontitis General Medicine Metabolism medicine.disease Chronic periodontitis Dentistry Section chemistry In vivo Transferrin Total iron-binding capacity Immunology Serum iron medicine business c.rectus Pcr analysis |
| Zdroj: | Journal of Clinical and Diagnostic Research, Vol 9, Iss 7, Pp ZC26-ZC30 (2015) |
| Popis: | BACKGROUND AND AIM: Periodontopathogens require iron constituents for their growth and metabolism in subgingival crevice. In this study, C.rectus was detected and quantified by using 16s rDNA based PCR in chronic periodontitis and compared with the levels of serum iron, total iron binding capacity and transferrin in chronic periodontitis and healthy sites. MATERIALS AND METHODS: One hundred twenty subjects divided into chronic periodontitis and healthy controls. Deep subgingival plaque was collected and genomic DNA was extracted from each sample analysed for C.rectus using 16s rRNA based PCR analysis. Blood samples were collected from both groups for estimation of serum iron, serum total iron binding capacity and serum transferrin levels. The quantified bacterial count was compared with blood samples. C. rectus was detected in both groups. RESULTS: There was significant increase in bacterial count in chronic periodontitis (p |
| Databáze: | OpenAIRE |
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