Prognostic Factors in the New Katagiri Scoring System After Palliative Surgery for Spinal Metastasis
| Autor: | Hiroaki Nakashima, Fumihiko Kato, Kei Ando, Atsuhiko Hirasawa, Hisatake Yoshihara, Kazuyoshi Kobayashi, Naoki Ishiguro, Shiro Imagama, Tokumi Kanemura, Koji Sato |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Palliative care Adolescent Metastasis Young Adult 03 medical and health sciences 0302 clinical medicine Lumbar Internal medicine medicine Humans Orthopedics and Sports Medicine Young adult Aged Retrospective Studies Aged 80 and over 030222 orthopedics Spinal Neoplasms Performance status business.industry Palliative Care Retrospective cohort study Middle Aged Decompression Surgical Prognosis medicine.disease Primary tumor Spine Hormonal therapy Female Neurology (clinical) business 030217 neurology & neurosurgery |
| Zdroj: | Spine. 45:E813-E819 |
| ISSN: | 1528-1159 0362-2436 |
| Popis: | STUDY DESIGN Retrospective study. OBJECTIVE The purpose of the study was to examine survival after surgery for a metastatic spinal tumor using prognostic factors in the new Katagiri score. SUMMARY OF BACKGROUND DATA Surgery for spinal metastasis can improve quality of life and facilitate treatment of the primary cancer. However, choice of therapy requires identification of prognostic factors for survival, and these may change over time due to treatment advances. The new Katagiri score for the prognosis of skeletal metastasis includes classification of the primary tumor site and the effects of chemotherapy and hormonal therapy. METHODS The subjects were 201 patients (127 males, 74 females) who underwent surgery for spinal metastases at six facilities in the Nagoya Spine Group. Age at surgery, gender, follow-up, metastatic spine level, primary cancer, new Katagiri score (including primary site, visceral metastasis, laboratory data, performance status (PS), and chemotherapy) and survival were obtained from a prospectively maintained database. RESULTS Posterior decompression (n = 29) and posterior decompression and fixation with instrumentation (n = 182) were performed at a mean age of 65.9 (range, 16-85) years. Metastasis was present in the cervical (n = 19, 10%), thoracic (n = 155, 77%), and lumbar (n = 26, 13%) spine, and sacrum (n = 1, 1%). In multivariate analysis, moderate growth (HR 2.95, 95% CI, 1.27-7.89, P |
| Databáze: | OpenAIRE |
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