Effects of PhD examination stress on allopregnanolone and cortisol plasma levels and peripheral benzodiazepine receptor density
| Autor: | Frank van Broekhoven, Frans G. Zitman, Paul N. Span, Hal A Droogleever Fortuyn, Robbert J. Verkes, Torbjörn Bäckström |
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| Rok vydání: | 2004 |
| Předmět: |
Adult
Blood Platelets Male medicine.medical_specialty Neuroactive steroid Hydrocortisone medicine.drug_class Endocrinology Diabetes and Metabolism education Hemodynamics Blood Pressure Pregnanolone chemistry.chemical_compound Endocrinology Cognitive neurosciences [UMCN 3.2] Heart Rate Reference Values Internal medicine Heart rate medicine Determinants in Health and Disease [EBP 1] Humans Biological Psychiatry Benzodiazepine Endocrine and Autonomic Systems Chemistry Endocrinology and reproduction [UMCN 5.2] Allopregnanolone Receptors GABA-A Psychiatry and Mental health Blood pressure Acute Disease Female Educational Measurement Glucocorticoid Stress Psychological medicine.drug |
| Zdroj: | Psychoneuroendocrinology, 29, 1341-4 Psychoneuroendocrinology, 29, 10, pp. 1341-4 |
| ISSN: | 0306-4530 |
| Popis: | Contains fulltext : 58623.pdf (Publisher’s version ) (Closed access) Peripheral benzodiazepine receptor (PBR) density in blood platelets and plasma allopregnanolone concentration in humans were determined following acute stress as represented by PhD examination. Fifteen healthy PhD students participated. Heart rate, blood pressure, plasma allopregnanolone, plasma cortisol, and PBR density were measured at different time points. Allopregnanolone and cortisol concentration and PBR density were significantly increased during examination. A positive correlation between allopregnanolone and PBR density was found. |
| Databáze: | OpenAIRE |
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