A randomized comparison of pupil-centered versus vertex-centered ablation in LASIK correction of hyperopia
| Autor: | Virginie Madariaga, Claire Triozon, François Malecaze, J.L. Arne, Pauline Soler, Vincent Soler, Pablo Artal, Antonio Benito |
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| Rok vydání: | 2010 |
| Předmět: |
Male
Visual acuity Corneal Wavefront Aberration genetic structures medicine.medical_treatment Keratomileusis Laser In Situ Visual Acuity Keratomileusis Refraction Ocular Pupil Cornea Double-Blind Method medicine Humans Corneal reflex Prospective Studies Coma Blinking business.industry Aberrometry Pupil size LASIK Middle Aged Ablation eye diseases Ophthalmology Hyperopia Optometry Female Lasers Excimer sense organs medicine.symptom business |
| Zdroj: | American journal of ophthalmology. 152(4) |
| ISSN: | 1879-1891 |
| Popis: | Purpose To compare visual and optical outcomes of pupil-centered vs vertex-centered ablation in patients undergoing laser-assisted in situ keratomileusis (LASIK) for hyperopia. Design Randomized, double-masked, prospective, single-center trial. Methods Setting: Institutional practice. Study population: Sixty eyes of 30 patients with low and moderate hyperopia. Intervention procedure: Eyes underwent LASIK (Allegretto excimer laser). In 30 eyes, the ablation was centered on the pupil, while in the 30 other eyes the ablation was centered on the corneal reflex. Main outcome measures: Primary outcome measure was the safety index. Main secondary outcome measures were efficacy index, manifest refraction, uncorrected visual acuity, best spectacle-corrected visual acuity (BCVA), and ocular high-order aberrations for a 6-mm pupil size. Results At 3 months postoperatively, the safety index was 0.99 ± 0.04 in the pupil-centered group and 0.99 ± 0.08 in the vertex-centered group ( P = .97). The efficacy index was also similar for both groups: 0.96 ± 0.05 in pupil-centered eyes and 0.93 ± 0.09 in vertex-centered eyes ( P = .31). Optical aberrations were similar for pupil-centered and vertex-centered eyes. Considering only eyes showing large pupil decentration, we found a tendency for better visual results in favor of pupil-centered eyes in terms of safety index and a slight but significant increase of coma in vertex-centered eyes. Conclusion LASIK is an effective procedure for treatment of hyperopia. Pupil-centered and vertex-centered treatments provide similar visual and optical outcomes. However, in eyes showing large temporal pupil decentration, pupil-centered ablation seemed to produce a lower amount of coma and, as a consequence, a reduced loss of BCVA compared with vertex-centered patients. |
| Databáze: | OpenAIRE |
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