Methylation status in females with rett syndrome
| Autor: | Adolf Muehl, Anne Moritz, Michael Freilinger, Oskar A. Haas, David Kalisch, Olaf Bodamer |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Adult
medicine.medical_specialty Homocysteine Adolescent Methyl-CpG-Binding Protein 2 Urine creatine Creatine metabolism Rett syndrome Biology Methylation 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Folic Acid Methionine 030225 pediatrics Internal medicine medicine Rett Syndrome Humans Child Creatinine medicine.disease Creatine Endocrinology chemistry Child Preschool Pediatrics Perinatology and Child Health Female Neurology (clinical) 030217 neurology & neurosurgery |
| Zdroj: | Journal of child neurology. 22(5) |
| ISSN: | 0883-0738 |
| Popis: | The authors studied methionine and creatine metabolism in females with Rett syndrome. Plasma metabolites (including methionine, homocysteine, guanidinoacetate) and urine creatine/creatinine ratios in 29 females with Rett syndrome were within the age-appropriate range. Although the authors have not been able to identify any abnormalities, it can be speculated that patients with Rett syndrome may benefit from dietary intervention to increase the supply of labile methyl groups to affected tissues. |
| Databáze: | OpenAIRE |
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