| Autor: |
Kenzo Soejima, Katsuhiko Naoki, Ichiro Kawada, Shinnosuke Ikemura, Hideki Terai, Tadashi Manabe, Keita Masuzawa, Junko Hamamoto, Tetsuo Tani, Keigo Kobayashi, Hiroyuki Yasuda, Ayano Oashi |
| Rok vydání: |
2023 |
| DOI: |
10.1158/1535-7163.22506109 |
| Popis: |
Figure S1 Synergistic efficacy of afatinib and cetuximab combination therapy Figure S2 Efficacy of EGFR-TKIs and cetuximab combination therapy Figure S3 Effect of EGFR tyrosine kinase inhibitors on EGFR monomer dimer equilibrium Figure S4 Dimerization of EGFR by EGF Figure S5 Proliferation of Ba/F3 cells with indicated EGFR genotypes in vitro Figure S6 Detection of monomer or dimer of EGFR in NIH-3T3 cells by immunoblotting Figure S7 Synergistic efficacy of dacomitinib and cetuximab combination therapy Figure S8 Monomer preference of dacomitinib Figure S9 Effect of the combination therapy in vivo model Figure S10 Evaluation of the cell surface EGFR expression level after drug treatment by flow cytometric analysis Figure S11 Efficacy of the afatinib and cetuximab combination therapy in osimertinib resistant cell lines |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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