Neutrophil/lymphocyte ratio predicts in‐hospital complications in Takotsubo syndrome. Results from a prospective multi‐center registry
| Autor: | Tecla Zimotti, Matteo Di Biase, Michele Cannone, Adriana Mallardi, Alessandra Leopizzi, Francesca Guastafierro, Francesco Santoro, Natale Daniele Brunetti |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty complications Neutrophils Clinical Investigations 030204 cardiovascular system & hematology Ventricular Function Left apical ballooning syndrome 03 medical and health sciences Leukocyte Count 0302 clinical medicine Takotsubo Cardiomyopathy Internal medicine medicine Humans 030212 general & internal medicine Lymphocytes Prospective Studies Registries Mean platelet volume Stroke Aged Heart Failure Ejection fraction business.industry Incidence (epidemiology) Cardiogenic shock Incidence Stroke Volume General Medicine Odds ratio medicine.disease Pulmonary edema Prognosis hemogram Italy ROC Curve Heart failure Cardiology neutrophil/lymphocyte ratio Female Cardiology and Cardiovascular Medicine business Takotsubo syndrome Follow-Up Studies |
| Zdroj: | Clinical Cardiology |
| ISSN: | 1932-8737 0160-9289 |
| Popis: | Background Several hematological indices including subtypes of leukocytes populations have been associated with cardiovascular outcome. Takotsubo syndrome (TTS) is a form of acute heart failure syndrome featured by several in‐hospital complications (IHCs). Hypothesis Hematological indices at admission may predict IHCs in TTS patients. Methods One hundred and sixty consecutive patients with TTS were enrolled in a multicenter prospective registry. Clinical data, admission hemogram, and IHCs were recorded. Results Incidence of IHCs was 37%, including pulmonary edema 9%, cardiogenic shock 9%, need of invasive ventilation 10%, death 8%, stroke 2.5%, and left ventricular thrombi 6%. Patients with IHCs were older, more frequently male, with physical stressor‐induced TTS, lower left ventricular ejection fraction at admission. Neutrophil/lymphocyte ratio (NLr) (12 ± 12 vs 7 ± 8, P = .002) and white blood cells/mean platelet volume ratio (1.2 ± 0.5 vs 1.0 ± 0.5, P = .03) at admission were significantly higher in patients with IHCs. NLr values were predictor of IHCs (Odds ratios [OR] 1.07, 95% CI 1.03‐1.11, P |
| Databáze: | OpenAIRE |
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