The oxygen content of coronary venous blood as affected by anoxia and cytochrome C

Autor: Joseph H. Hafkenschiel, James E. Eckenhoff
Rok vydání: 1948
Předmět:
Zdroj: American Heart Journal. 36:893-898
ISSN: 0002-8703
DOI: 10.1016/0002-8703(48)90282-8
Popis: 1. 1. By means of the bubble flowmeter and the coronary sinus catheterization methods of investigating the coronary circulation of the dog, the “normal” values for the coronary venous oxygen content have been found to be 3 to 6 volumes per cent. 2. 2. When 8 to 10 per cent oxygen mixtures were breathed, the oxygen content of coronary venous blood was reduced to 2 volumes per cent or less. 3. 3. Increases in oxygen uptake by the heart were accomplished primarily by increases in the volume of coronary blood flow. 4. 4. Cytochrome C, when injected intravenously in amounts varying from 3.8 to 12.5 mg. per kilogram of body weight, did not increase the coronary arteriovenous oxygen difference or the oxygen uptake of the heart.
Databáze: OpenAIRE