Adenosine provokes diastolic dysfunction in microvascular angina
| Autor: | Ann C. Tweddel, A. Lee, Alan Gordon Fraser, M. Robinson, D. Vinereanu |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Male
medicine.medical_specialty Adenosine Vasodilator Agents Diastole Pilot Projects Chest pain Ventricular Dysfunction Left Tissue Doppler echocardiography Internal medicine medicine Humans cardiovascular diseases Microvascular Angina Echocardiography Doppler Pulsed medicine.diagnostic_test business.industry Microvascular angina Gated Blood-Pool Imaging General Medicine Middle Aged Blood pressure Angiography cardiovascular system Cardiology Original Article Female medicine.symptom business Echocardiography Stress medicine.drug |
| Zdroj: | Postgraduate Medical Journal. 78:40-42 |
| ISSN: | 1469-0756 0032-5473 |
| DOI: | 10.1136/pmj.78.915.40 |
| Popis: | Adenosine stress echocardiography was performed in nine patients (58 (±3) years, eight women) with documented microvascular angina. Global ventricular function was assessed by Tc99m blood pool imaging and Doppler, whereas longitudinal ventricular function was assessed by simultaneous tissue Doppler echocardiography of the lateral mitral annulus. Adenosine was infused incrementally to onset of chest pain in all patients. There was no significant change in global or longitudinal systolic function. Adenosine induced global diastolic dysfunction, demonstrated by blood pool imaging and by Doppler of the transmitral flow. All patients had long axis diastolic dysfunction at peak adenosine, revealed by a ratio of early to late diastolic velocity of lateral mitral annulus |
| Databáze: | OpenAIRE |
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