Pituitary Adenoma Combined with Rathke's Cleft Cyst —Case Report

Autor: Goro Kido, Tadashi Shibuya, Hidehiko Kushi, Miyagi A, Mitsuyoshi Iwasaki, Takashi Tsubokawa, Mitsusuke Miyagami
Rok vydání: 1993
Předmět:
Zdroj: Neurologia medico-chirurgica. 33:643-650
ISSN: 1349-8029
0470-8105
Popis: A rare pituitary adenoma associated with Rathke's cleft cyst was discovered incidentally in a 44-year-old male admitted after head trauma. Neurological and physiological examination found no abnormalities, except for panhypopituitarism. Computed tomography and magnetic resonance imaging demonstrated a solid mass in the sellar cavity with suprasellar extension, associated with a cystic mass extending into the third ventricle. The tumor was removed subtotally by the transcranial approach. Light microscopy demonstrated that the cyst wall was composed of ciliated columnar cells, cuboidal cells, and goblet cells, and the solid part indicated chromophobe pituitary adenoma. Immunohistochemistry demonstrated that a few adenoma cells were positive for prolactin and the cyst wall cells were positive for cytokeratin and negative for S-100 protein.
Databáze: OpenAIRE