Primary hypoparathyroidism in two horses
| Autor: | D. B. Church, J Trevena, Darren Hodgson, N. P. H. Hudson, I L Nielsen, D Major |
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| Rok vydání: | 1999 |
| Předmět: |
Male
medicine.medical_specialty Hypoparathyroidism chemistry.chemical_element Parathyroid hormone Calcium Gastroenterology Diagnosis Differential Fatal Outcome Internal medicine Synchronous diaphragmatic flutter Animals Humans Medicine Hypocalcaemia Horses General Veterinary business.industry Horse General Medicine medicine.disease Endocrinology chemistry Female Horse Diseases business Dihydrotachysterol medicine.drug Primary Hypoparathyroidism |
| Zdroj: | Australian Veterinary Journal. 77:504-508 |
| ISSN: | 0005-0423 |
| DOI: | 10.1111/j.1751-0813.1999.tb12119.x |
| Popis: | Two Thoroughbred horses were presented with various clinical signs which included sweating, agitation, muscle twitching and synchronous diaphragmatic flutter. These signs were associated with profound hypocalcaemia. A diagnosis of primary hypoparathyroidism was made on the basis of low serum ionised calcium concentration, hyperphosphataemia and markedly reduced serum immunoreactive parathyroid hormone concentrations in the presence of normal renal function. Treatment with a combination of intravenous calcium and subsequently oral calcium, magnesium and a vitamin D analogue (dihydrotachysterol) for up to 65 days resulted in complete remission of clinical signs. Horse 1 was euthanased 12 months after the initial recognition of signs. Results of necropsy were unremarkable apart from an absence of detectable parathyroid tissue. Horse 2 returned to athletic activities while receiving only maintenance doses of oral calcium carbonate. |
| Databáze: | OpenAIRE |
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