Prospective analysis on brain magnetic resonance imaging in children
| Autor: | Klaus Schmitt, Ariane Biebl, Brigitte Povysil, Christine M. Fellner, Dieter Furthner, Margit Ehrenmüller, Franz A. Fellner, Bettina Frechinger |
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| Rok vydání: | 2014 |
| Předmět: |
Male
medicine.medical_specialty Pediatrics Adolescent Concordance Neurological examination Electroencephalography Prospective analysis medicine Prevalence Humans Brain magnetic resonance imaging Prospective Studies Prospective cohort study Child Pathological Retrospective Studies Neurologic Examination Brain Diseases Incidental Findings medicine.diagnostic_test business.industry Brain Infant General Medicine Magnetic Resonance Imaging Child Preschool Pediatrics Perinatology and Child Health Female Neurology (clinical) Radiology business Paediatric population |
| Zdroj: | European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society. 19(3) |
| ISSN: | 1532-2130 |
| Popis: | Background Previous studies have addressed the prevalence of incidental findings in adult populations. There are few studies following paediatric patients, most of data were retrieved retrospectively. We conducted a prospective study to determine the prevalence of incidental, pathologic and normal findings in a symptomatic paediatric population. Methods The subjects of this prospective single centre study are 436 children aged 0–18 years with clinical symptoms and subsequent first brain MRI. Normal, incidental as well as pathologic MRI findings are documented in association with age, gender, neurological examination and previous investigations (CCT, EEG). Secondary outcome parameters are defined as MRI results and their implications. Two board-certified radiologists prospectively analysed MR images without knowing the result from each other. Results The 436 patients with brain MRI were categorized into three groups as follows: 155 (35.5%) patients had normal findings, 163 (37.4%) had incidental findings and 118 (27.1%) had pathological findings in brain MRI. When adding patients with pathologic and incidental findings we report even more (47.9%). We analysed the correlation between neurologic examination and MRI result and it was significant (p-value 0.0008). The p-value for concordance of both radiology reports was Conclusion To our knowledge this is the first prospective paediatric study reporting the prevalence of normal, pathologic and incidental findings in brain MRI in symptomatic children. Incidental findings are common in paediatric patients but we report the highest prevalence. Our data may help guiding management decision in a consistent and clinically appropriate manner. |
| Databáze: | OpenAIRE |
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