Additional file 2 of A polo-like kinase inhibitor identified by computational repositioning attenuates pulmonary fibrosis

Autor: Imakura, Takeshi, Sato, Seidai, Koyama, Kazuya, Ogawa, Hirohisa, Niimura, Takahiro, Murakami, Kojin, Yamashita, Yuya, Haji, Keiko, Naito, Nobuhito, Kagawa, Kozo, Kawano, Hiroshi, Zamami, Yoshito, Ishizawa, Keisuke, Nishioka, Yasuhiko
Rok vydání: 2023
DOI: 10.6084/m9.figshare.23290345
Popis: Additional file 2: Figure E1. BI2536, a PLK1/2 inhibitor, showed a tendency to attenuate pulmonary fibrosis. Figure E2. PLK1 expression in alveolar type 2 cells and PLK2 expression in myofibroblast. Figure E3. The analysis of bronchoalveolar lavage fluid in mice treated with bleomycin and GSK461364. Figure E4. BI2536 downregulates the mRNA expression of Col1a1. Figure E5. Expanded blots from Figure 6C. Figure E6. Expanded blots from Figure 6F.
Databáze: OpenAIRE