Intermittent hypoxia increases exercise tolerance in elderly men with and without coronary artery disease
| Autor: | Elena Tkatchouk, Igor Ehrenbourg, Reinhard Pühringer, Martin Faulhaber, Günther Mitterbauer, Martin Burtscher, Otmar Pachinger |
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| Rok vydání: | 2004 |
| Předmět: |
Male
medicine.medical_specialty Physical exercise Coronary Artery Disease Risk Assessment Coronary artery disease Oxygen Consumption Double-Blind Method Reference Values Internal medicine Heart rate medicine Humans Myocardial infarction Exercise physiology Hypoxia Exercise Aged Exercise Tolerance business.industry Intermittent hypoxia Middle Aged Hypoxia (medical) medicine.disease Surgery Blood pressure Exercise Test Cardiology medicine.symptom Cardiology and Cardiovascular Medicine business Follow-Up Studies |
| Zdroj: | International Journal of Cardiology. 96:247-254 |
| ISSN: | 0167-5273 |
| DOI: | 10.1016/j.ijcard.2003.07.021 |
| Popis: | Background: Intermittent hypoxia has been suggested to increase exercise tolerance by enhancing stress resistance and improving oxygen delivery. Because the improvement of exercise tolerance reduces mortality in the elderly with and without coronary artery disease intermittent hypoxia might be a valuable preventive and therapeutic tool. However, controlled studies are lacking. Methods and results: Sixteen males (50–70 years, 8 with and 8 without prior myocardial infarction) were randomly assigned in a double-blind fashion to receive 15 sessions of passive intermittent hypoxia (hypoxia group) or normoxia (control group) within 3 weeks. For the hypoxia group each session consisted of three to five hypoxic (14–10% oxygen) periods (3–5 min) with 3-min normoxic intervals. Controls inhaled only normoxic air in the same way. Exercise tests were performed before and after the 3-week breathing program. After 3 weeks of intermittent hypoxia peak oxygen consumption had increased compared to normoxic conditions (+6.2% vs.3%, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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