Chemodivergent synthesis of multi-substituted/fused pyrroles via copper-catalyzed carbene cascade reaction of propargyl α-iminodiazoacetates
| Autor: | Sailan Chang, Cheng Zhang, Xinfang Xu, Lihua Qiu |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
010405 organic chemistry
Stereochemistry Chemistry Metals and Alloys Substrate (chemistry) General Chemistry 010402 general chemistry 01 natural sciences Combinatorial chemistry Catalysis 0104 chemical sciences Surfaces Coatings and Films Electronic Optical and Magnetic Materials chemistry.chemical_compound Cascade reaction Propargyl Materials Chemistry Ceramics and Composites Copper catalyzed Carbene |
| Zdroj: | Chemical communications (Cambridge, England). 52(84) |
| ISSN: | 1364-548X |
| Popis: | A novel cascade reaction of alkynyl-tethered α-iminodiazoacetates has been developed, which provides a general access to both multi-substituted and fused pyrroles in high yields with a broad substrate scope. The γ-imino carbene is proposed as the key intermediate in this divergent reaction and followed by unpresented transformations. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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