Expression patterns of the netrin receptor UNC5H1 among developing motor neurons in the embryonic rat hindbrain
Autor: | Sarah Guthrie, Camilla Barrett |
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Rok vydání: | 2001 |
Předmět: |
Embryology
animal structures Gene Expression Receptors Cell Surface Hindbrain Netrin receptor Biology Chemorepulsion Netrin medicine Animals Receptor In Situ Hybridization reproductive and urinary physiology Motor Neurons Gene Expression Profiling fungi Anatomy Motor neuron Embryonic stem cell Rats Rhombencephalon Genes DCC medicine.anatomical_structure nervous system embryonic structures Axon guidance Netrin Receptors Neuroscience Developmental Biology |
Zdroj: | Mechanisms of Development. 106(1-2):163-166 |
ISSN: | 0925-4773 |
DOI: | 10.1016/s0925-4773(01)00415-4 |
Popis: | The axon guidance molecule netrin-1 has been implicated in the midline repulsion of developing cranial motor axons. We have examined expression patterns of the netrin receptors UNC5H1 and DCC in embryonic rat hindbrains, in combination with labelling of developing motor neurons. We found that UNC5H1 expression colocalised with a number of cranial motor neuron subpopulations from embryonic day 11 (E11) to E14, while DCC was expressed by motor neurons at E12. |
Databáze: | OpenAIRE |
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