The draft genome of whitefly Bemisia tabaci MEAM1, a global crop pest, provides novel insights into virus transmission, host adaptation, and insecticide resistance
| Autor: | Angela E. Douglas, Murad Ghanim, Marcus C. Stensmyr, Yi Zheng, Wayne B. Hunter, Adi Kliot, Xiaowei Yang, Patricia V. Pinheiro, Georg Jander, Alvin M. Simmons, Wenli Liu, Navneet Kaur, Jun-Bo Luan, Honghe Sun, Tonja W. Fisher, Yuan Luo, Judith K. Brown, Angela Kruse, Zhangjun Fei, Galina Lebedev, Kai Shu Ling, Michelle Cilia, Daniel K. Hasegawa, David R. Nelson, Wenbo Chen, William M. Wintermantel, Svetlana Kontsedalov, Yimin Xu |
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| Přispěvatelé: | WENBO CHEN, DANIEL K. HASEGAWA, NAVNEET KAUR, ADI KLIOT, PATRICIA VALLE PINHEIRO, CNPAF, JUNBO LUAN, M. C. STENSMYR, YI ZHENG, WENLI LIU, HONGHE SUN, YIMIN XU, YUAN LUO, ANGELA KRUSE, XIAOWEI YANG, SVETLANA KONTSEDALOV, GALINA LEBEDEV, TONJA W. FISHER, DAVID R. NELSON, WAYNE B. HUNTER, JUDITH K. BROWN, GEORG JANDER, MICHELLE CILIA, ANGELA E. DOUGLAS, MURAD GHANIM, ALVIN M. SIMMONS, WILLIAM M. WINTERMANTEL, KAI-SHU LING, ZHANGJUN FEI. |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0106 biological sciences
0301 basic medicine Physiology Genome Insect Plant Science 01 natural sciences Genome Bemisia tabaci Plant Viruses Insecticide Resistance Structural Biology 2. Zero hunger Genetics Agricultural and Biological Sciences(all) biology Polyphagy Biological Sciences Whitefly Infectious Diseases Praga de planta Draft genome Insect Proteins Zero Hunger Host adaptation General Agricultural and Biological Sciences Infection Plant pests Biotechnology Research Article Insecticide resistance General Biochemistry Genetics and Molecular Biology Virus transmission Hemiptera 03 medical and health sciences Plant virus Botany Gene family Animals Gene Ecology Evolution Behavior and Systematics Synteny Whole genome sequencing Biochemistry Genetics and Molecular Biology(all) Cell Biology 15. Life on land biology.organism_classification 010602 entomology 030104 developmental biology Mosca branca Insect Developmental Biology |
| Zdroj: | BMC Biology BMC biology, vol 14, iss 1 Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA-Alice) Empresa Brasileira de Pesquisa Agropecuária (Embrapa) instacron:EMBRAPA |
| ISSN: | 1741-7007 |
| Popis: | Background The whitefly Bemisia tabaci (Hemiptera: Aleyrodidae) is among the 100 worst invasive species in the world. As one of the most important crop pests and virus vectors, B. tabaci causes substantial crop losses and poses a serious threat to global food security. Results We report the 615-Mb high-quality genome sequence of B. tabaci Middle East-Asia Minor 1 (MEAM1), the first genome sequence in the Aleyrodidae family, which contains 15,664 protein-coding genes. The B. tabaci genome is highly divergent from other sequenced hemipteran genomes, sharing no detectable synteny. A number of known detoxification gene families, including cytochrome P450s and UDP-glucuronosyltransferases, are significantly expanded in B. tabaci. Other expanded gene families, including cathepsins, large clusters of tandemly duplicated B. tabaci-specific genes, and phosphatidylethanolamine-binding proteins (PEBPs), were found to be associated with virus acquisition and transmission and/or insecticide resistance, likely contributing to the global invasiveness and efficient virus transmission capacity of B. tabaci. The presence of 142 horizontally transferred genes from bacteria or fungi in the B. tabaci genome, including genes encoding hopanoid/sterol synthesis and xenobiotic detoxification enzymes that are not present in other insects, offers novel insights into the unique biological adaptations of this insect such as polyphagy and insecticide resistance. Interestingly, two adjacent bacterial pantothenate biosynthesis genes, panB and panC, have been co-transferred into B. tabaci and fused into a single gene that has acquired introns during its evolution. Conclusions The B. tabaci genome contains numerous genetic novelties, including expansions in gene families associated with insecticide resistance, detoxification and virus transmission, as well as numerous horizontally transferred genes from bacteria and fungi. We believe these novelties likely have shaped B. tabaci as a highly invasive polyphagous crop pest and efficient vector of plant viruses. The genome serves as a reference for resolving the B. tabaci cryptic species complex, understanding fundamental biological novelties, and providing valuable genetic information to assist the development of novel strategies for controlling whiteflies and the viruses they transmit. Electronic supplementary material The online version of this article (doi:10.1186/s12915-016-0321-y) contains supplementary material, which is available to authorized users. |
| Databáze: | OpenAIRE |
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