Nephelometric method for determination of rheumatoid factor

Autor:	Gabriel Virella, H. Hugh Fudenberg, Marion Waller
Rok vydání:	1978
Předmět:	Chromatography Serial dilution Chemistry Immunology Light scattering Dilution Latex fixation test Titer Nephelometry and Turbidimetry Rheumatoid Factor Humans Immunology and Allergy Rheumatoid factor Latex Fixation Tests
Zdroj:	Journal of Immunological Methods. 22:247-251
ISSN:	0022-1759
DOI:	10.1016/0022-1759(78)90032-7
Popis:	We have developed a nephelometric technique for determining titers of rheumatoid factor. Serum dilutions are added to a mixture of commercially available latex particles of small size (0.098 micrometer) and human gamma-globulin. Rheumatoid sera induce a substantial increase in the light scattering properties of the mixture, and the highest dilution significantly increasing the light scattering is considered as the titer for that serum. This technique is simple to use, provides objective results, and can be automated for analysis of large numbers of samples.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::474cd213b4ee3e8d9c9e8402c2f9d7f1 https://doi.org/10.1016/0022-1759(78)90032-7 Zobrazit plný text záznamu