Comparison of amplitude-decorrelation, speckle-variance and phase-variance OCT angiography methods for imaging the human retina and choroid
| Autor: | Robert J. Zawadzki, Arlie G. Capps, Justin V Migacz, Iwona Gorczynska, John S. Werner |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Materials science
genetic structures (170.3880) Medical and biological imaging Bioengineering Image processing Optical Physics Eye 01 natural sciences Article 010309 optics 03 medical and health sciences Speckle pattern chemistry.chemical_compound 0302 clinical medicine Optics (110.4500) Optical coherence tomography (170.4470) Ophthalmology Optical coherence tomography 0103 physical sciences medicine Eye Disease and Disorders of Vision Decorrelation Retina medicine.diagnostic_test business.industry (110.2960) Image analysis Neurosciences Speckle noise Retinal (110.0110) Imaging systems Materials Engineering (280.2490) Flow diagnostics Atomic and Molecular Physics and Optics eye diseases medicine.anatomical_structure chemistry 030221 ophthalmology & optometry Biomedical Imaging Choroid sense organs business Biotechnology Biomedical engineering |
| Zdroj: | Biomedical optics express, vol 7, iss 3 Gorczynska, I; Migacz, JV; Zawadzki, RJ; Capps, AG; & Werner, JS. (2016). Comparison of amplitude-decorrelation, specklevariance and phase-variance OCT angiography methods for imaging the human retina and choroid. Biomedical Optics Express, 7(3), 911-942. doi: 10.1364/BOE.7.000911. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/1j84v90j |
| DOI: | 10.1364/BOE.7.000911. |
| Popis: | © 2016 Optical Society of America. We compared the performance of three OCT angiography (OCTA) methods: speckle variance, amplitude decorrelation and phase variance for imaging of the human retina and choroid. Two averaging methods, split spectrum and volume averaging, were compared to assess the quality of the OCTA vascular images. All data were acquired using a swept-source OCT system at 1040 nm central wavelength, operating at 100,000 A-scans/s. We performed a quantitative comparison using a contrast-to-noise (CNR) metric to assess the capability of the three methods to visualize the choriocapillaris layer. For evaluation of the static tissue noise suppression in OCTA images we proposed to calculate CNR between the photoreceptor/RPE complex and the choriocapillaris layer. Finally, we demonstrated that implementation of intensity-based OCT imaging and OCT angiography methods allows for visualization of retinal and choroidal vascular layers known from anatomic studies in retinal preparations. OCT projection imaging of data flattened to selected retinal layers was implemented to visualize retinal and choroidal vasculature. User guided vessel tracing was applied to segment the retinal vasculature. The results were visualized in a form of a skeletonized 3D model. |
| Databáze: | OpenAIRE |
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