MORPHOLOGICAL CHANGES IN MICE LIVER IN DYNAMICS OF CONCANAVALIN A - INDUCED HEPATITIS
| Autor: | N G Grushka, R I Janchiy, Tatyana Bryzgina, N V Makogon, S I Pavlovych |
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| Rok vydání: | 2015 |
| Předmět: |
Male
Pathology medicine.medical_specialty Leukocyte migration Physiology Neutrophile Population Hepatitis Animal Autoantigens Monocytes Microcirculation Mice Immune system Concanavalin A medicine Animals Lymphocytes Hematoxylin education Hepatitis education.field_of_study Histocytochemistry Chemistry Macrophages Acquired immune system medicine.disease Liver Neutrophil Infiltration Mice Inbred CBA Eosine Yellowish-(YS) Infiltration (medical) |
| Zdroj: | Fiziolohichnyĭ zhurnal. 62:83-91 |
| ISSN: | 0201-8489 |
| Popis: | The injure of the liver tissue and its infiltration by cells of the innate and adaptive immunity in dynamics of Con A-induced hepatitis in mice was studied. The semiquantitative method of damage rate of microcirculation channel and liver parenchyma was used, leukocyte liver infiltration and cellular composition of infiltrates were investigated also. Primary liver reaction to the Con-A was the inflammatory changes in the vascular bed, followed by disturbances in the parenchyma.The sufficient increasing of leukocyte migration to the liver was revealed. Besides, the neutrophile infiltration was increased first with a maximum at 6 hours of the experiment (63,9 ±4,6%, p |
| Databáze: | OpenAIRE |
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