Investigating feasibility of 2021 WHO protocol for cervical cancer screening in underscreened populations: PREvention and SCReening Innovation Project Toward Elimination of Cervical Cancer (PRESCRIP-TEC)
| Autor: | Marat Sultanov, Janine de Zeeuw, Jaap Koot, Jurjen van der Schans, Jogchum J. Beltman, Marlieke de Fouw, Marek Majdan, Martin Rusnak, Naheed Nazrul, Aminur Rahman, Carolyn Nakisige, Arathi P. Rao, Keerthana Prasad, Shyamala Guruvare, Regien Biesma, Marco Versluis, Geertruida H. de Bock, Jelle Stekelenburg |
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| Přispěvatelé: | Research programme EEF, Public Health Research (PHR), Basic and Translational Research and Imaging Methodology Development in Groningen (BRIDGE), Damage and Repair in Cancer Development and Cancer Treatment (DARE), Life Course Epidemiology (LCE) |
| Jazyk: | angličtina |
| Předmět: |
Bangladesh
Slovakia Papillomavirus Infections Public Health Environmental and Occupational Health Uterine Cervical Neoplasms India Papillomavirus Infections/diagnosis World Health Organization Mass Screening/methods Artificial Intelligence Uterine Cervical Neoplasms/diagnosis Implementation Cervical cancer Mass Screening Feasibility Studies Humans Female Cervical cancer screening Uganda Early Detection of Cancer/methods Papillomaviridae Early Detection of Cancer Human papillomavirus testing |
| Zdroj: | BMC Public Health, 22(1):1356. BMC BMC Public Health, 22(1). BMC BMC Public Health |
| ISSN: | 1471-2458 |
| DOI: | 10.1186/s12889-022-13488-z |
| Popis: | Background High-risk human papillomavirus (hrHPV) testing has been recommended by the World Health Organization as the primary screening test in cervical screening programs. The option of self-sampling for this screening method can potentially increase women’s participation. Designing screening programs to implement this method among underscreened populations will require contextualized evidence. Methods PREvention and SCReening Innovation Project Toward Elimination of Cervical Cancer (PRESCRIP-TEC) will use a multi-method approach to investigate the feasibility of implementing a cervical cancer screening strategy with hrHPV self-testing as the primary screening test in Bangladesh, India, Slovak Republic and Uganda. The primary outcomes of study include uptake and coverage of the screening program and adherence to follow-up. These outcomes will be evaluated through a pre-post quasi-experimental study design. Secondary objectives of the study include the analysis of client-related factors and health system factors related to cervical cancer screening, a validation study of an artificial intelligence decision support system and an economic evaluation of the screening strategy. Discussion PRESCRIP-TEC aims to provide evidence regarding hrHPV self-testing and the World Health Organization’s recommendations for cervical cancer screening in a variety of settings, targeting vulnerable groups. The main quantitative findings of the project related to the impact on uptake and coverage of screening will be complemented by qualitative analyses of various determinants of successful implementation of screening. The study will also provide decision-makers with insights into economic aspects of implementing hrHPV self-testing, as well as evaluate the feasibility of using artificial intelligence for task-shifting in visual inspection with acetic acid. Trial registration ClinicalTrials.gov, NCT05234112. Registered 10 February 2022 |
| Databáze: | OpenAIRE |
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