Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 2: Aminoglycosides/aminocyclitols: apramycin, paromomycin, neomycin and spectinomycin

Autor: EFSA Panel on Biological Hazards (BIOHAZ), Allende, Ana, Koutsoumanis, Konstantinos, Alvarez-Ordóñez, Avelino, Bolton, Declan, Bover-Cid, Sara, Chemaly, Marianne, Davies, Robert, De Cesare, Alessandra, Herman, Lieve, Hilbert, Friederike, Lindqvist, Roland, Nauta, Maarten, Ru, Giuseppe, Simmons, Marion, Skandamis, Panagiotis, Suffredini, Elisabetta, Andersson, Dan I, Bampidis, Vasileios, Bengtsson-Palme, Johan, Bouchard, Damien, Ferran, Aude, Kouba, Maryline, López Puente, Secundino, López-Alonso, Marta, Nielsen, Søren Saxmose, Pechová, Alena, Petkova, Mariana, Girault, Sebastien, Broglia, Alessandro, Guerra, Beatriz, Innocenti, Matteo Lorenzo, Liébana, Ernesto, López-Gálvez, Gloria, Manini, Paola, Stella, Pietro, Peixe, Luisa
Přispěvatelé: Allende A., Koutsoumanis K., Alvarez-Ordoñez A., Bolton D., Bover-Cid S., Chemaly M., Davies R., De Cesare A., Herman L., Hilbert F., Lindqvist R., Nauta M., Ru G., Simmons M., Skandamis P., Suffredini E., Andersson D.I., Bampidis V., Bengtsson-Palme J., Bouchard D., Ferran A., Kouba M., Lopez Puente S., Lopez-Alonso M., Nielsen S.S., Pechova A., Petkova M., Girault S., Broglia A., Guerra B., Innocenti M.L., Liebana E., Lopez-Galvez G., Manini P., Stella P., Peixe L., Indústries Alimentàries, Funcionalitat i Seguretat Alimentària
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: IRTA Pubpro. Open Digital Archive
Institut de Recerca i Tecnologia Agroalimentàries (IRTA)
EFSA Journal, Vol 19, Iss 10, Pp n/a-n/a (2021)
EFSA Panel on Biological Hazards (BIOHAZ), Allende, A, Koutsoumanis, K, Allende, A, Alvarez-Ordóñez, A, Bolton, D, Bover-Cid, S, Chemaly, M, Davies, R, De Cesare, A, Herman, L, Hilbert, F, Lindqvist, R, Nauta, M, Ru, G, Simmons, M, Skandamis, P, Suffredini, E, Andersson, D I, Bampidis, V, Bengtsson-Palme, J, Bouchard, D, Ferran, A, Kouba, M, López Puente, S, López-Alonso, M, Nielsen, S S, Pechová, A, Petkova, M, Girault, S, Broglia, A, Guerra, B, Innocenti, M L, Liébana, E, López-Gálvez, G, Manini, P, Stella, P & Peixe, L 2021, ' Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 2: Aminoglycosides/aminocyclitols: apramycin, paromomycin, neomycin and spectinomycin ', EFSA Journal, vol. 19, no. 10, e06853, pp. 1-39 . https://doi.org/10.2903/j.efsa.2021.6853
Popis: The specific concentrations of apramycin, paromomycin, neomycin and spectinomycin in non-target feed for food-producing animals, below which there would not be an effect on the emergence of, and/or selection for, resistance in bacteria relevant for human and animal health, as well as the specific antimicrobial concentrations in feed which have an effect in terms of growth promotion/increased yield, were assessed by EFSA in collaboration with EMA. Details of the methodology used for this assessment, associated data gaps and uncertainties, are presented in a separate document. To address antimicrobial resistance, the Feed Antimicrobial Resistance Selection Concentration (FARSC) model developed specifically for the assessment was applied. However, due to the lack of data on the parameters required to calculate the FARSC for these antimicrobials, it was not possible to conclude the assessment until further experimental data become available. To address growth promotion, data from scientific publications obtained from an extensive literature review were used. Levels in feed that showed to have an effect on growth promotion/increased yield were reported for apramycin and neomycin, whilst for paromomycin and spectinomycin, no suitable data for the assessment were available. It was recommended to carry out studies to generate the data that are required to fill the gaps which prevented the calculation of the FARSC for these four antimicrobials. info:eu-repo/semantics/publishedVersion
Databáze: OpenAIRE