Severe Necrotizing Pneumonia in Children: A Challenge to Intensive Care Specialist
| Autor: | Pradeep Kumar Aggarwal, Anand Singh Kushwaha, R. D. Srivastava, Girraj K. Aggarwal, Nikhil Vinayak, Pradeep Sharma |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Staphylococcus aureus Pleural effusion medicine.medical_treatment Bronchopleural fistula 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Intensive care Intensive Care Units Neonatal medicine Humans 030212 general & internal medicine Child Retrospective Studies Mechanical ventilation Respiratory Distress Syndrome Respiratory distress business.industry Infant Pneumothorax Pneumonia Length of Stay medicine.disease Respiration Artificial Empyema Anti-Bacterial Agents Pleural Effusion Infectious Diseases Pneumonia Necrotizing Child Preschool Pediatrics Perinatology and Child Health Intensive Care Neonatal Drainage Female business |
| Zdroj: | Journal of tropical pediatrics. 66(6) |
| ISSN: | 1465-3664 |
| Popis: | Objective Necrotizing pneumonia (NP) is recently recognized as a complication of pneumonia. The data on NP are scant from developing world and we aimed to describe the characteristic features of NP in our children. Study design Single center retrospective cohort analysis. Patient selection Institutional database of children treated for pneumonia between September 2014 and May 2018 was searched to identify children with NP. Methods The demographic characteristics, laboratory results, and clinical information were recorded for patients selected as NP and analyzed. Results In total, 10 patients (3.7%) of NP were identified out of 272 patients with pneumonia. Median age was 3 years (range: 3 months to 12years). All cases had severe respiratory distress and 70% required mechanical ventilation and inotropic support. The causative pathogens were identified in 6/10 children (60%) with Staphylococcus aureus being most common (4/10). Pleural effusion and pneumothorax were seen in six cases. Four cases had bilateral pleural effusion and three had bilateral pneumothorax. Intercostal drainage (ICD) was placed in 70% and bilateral ICD was placed in 40% cases. Bronchopleural fistula (BPF) developed in two cases and one had bilateral BPF. Median [inter quartile range] ICD days and hospital stay were 9 (6–14) and 13.5 (7.5–18.5) days, respectively. Mean (±SD) total antibiotic (in hospital plus outpatient) days were 28.8 ± 9.6 days. Four cases had airway hemorrhage and in three cases this was massive and fatal. Conclusion NP is a relatively rare but severe complication of pneumonia distinct from pediatric acute respiratory distress, pleural effusion and empyema. Airway hemorrhage is the most fatal complication. |
| Databáze: | OpenAIRE |
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