Clinical Outcome Predictive Value of Procalcitonin in Patients Suspected with Infection in the Emergency Department
| Autor: | Sebastien De Ruffi, Laurent Ramont, Pierre Leroux, Marion Gornet, Stéphane Gennai, Guillaume Giordano Orsini, Lukshe Kanagaratnam, Xavier Losset |
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| Přispěvatelé: | Matrice extracellulaire et dynamique cellulaire - UMR 7369 (MEDyC), Université de Reims Champagne-Ardenne (URCA)-SFR CAP Santé (Champagne-Ardenne Picardie Santé), Université de Reims Champagne-Ardenne (URCA)-Université de Picardie Jules Verne (UPJV)-Université de Reims Champagne-Ardenne (URCA)-Université de Picardie Jules Verne (UPJV)-Centre National de la Recherche Scientifique (CNRS), Pathologies Pulmonaires et Plasticité Cellulaire - UMR-S 1250 (P3CELL), Université de Reims Champagne-Ardenne (URCA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Hospitalier Universitaire de Reims (CHU Reims) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Article Subject [SDV]Life Sciences [q-bio] Physical examination 030204 cardiovascular system & hematology Logistic regression Procalcitonin 03 medical and health sciences 0302 clinical medicine Internal medicine medicine medicine.diagnostic_test RC86-88.9 Septic shock business.industry Medical emergencies. Critical care. Intensive care. First aid 030208 emergency & critical care medicine Retrospective cohort study Odds ratio Emergency department medicine.disease 3. Good health Bacteremia Emergency Medicine business Research Article |
| Zdroj: | Emergency Medicine International Emergency Medicine International, 2021, 2021, pp.1-8. ⟨10.1155/2021/2344212⟩ Emergency Medicine International, Vol 2021 (2021) |
| ISSN: | 2090-2840 |
| DOI: | 10.1155/2021/2344212⟩ |
| Popis: | International audience; Procalcitonin (PCT) may be useful for early risk stratification in the emergency department (ED), but the transposition of published data to routine emergency practice is sometimes limited. An observational retrospective study was conducted in the adult ED of the Reims University Hospital (France). Over one year, 852 patients suspected of infection were included, of mean age 61.7 years (SD: 22.6), and 624 (73.2%) were hospitalized following ED visit. Overall, 82 (9.6%) patients died during their hospitalization with an odds ratio (OR) of 5.10 (95% CI: 2.19–11.87) for PCT ≥ 0.5, in multivariate logistic regression analyses. Moreover, 78 (9.2%) patients were admitted to an ICU, 74 (8.7%) had attributable bacteremia, and 56 (6.6%) evolved toward septic shock with an OR of 4.37 (2.08–9.16), 6.38 (2.67–15.24), and 6.38 (2.41–16.86), respectively, for PCT ≥ 0.5. The highest discriminatory values were found for patients with age |
| Databáze: | OpenAIRE |
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