Long-term economic evaluation of intensive patient education during the first treatment year in newly diagnosed adult asthma

Autor: R. Kauppinen, H. Tukiainen, Harri Sintonen, T. Klaukka, V. Vilkka
Rok vydání: 2001
Předmět:
Zdroj: Respiratory Medicine. 95:56-63
ISSN: 0954-6111
DOI: 10.1053/rmed.2000.0971
Popis: The cost-effectiveness of intensive patient education of guided asthma self-management given during the first treatment year was evaluated after 5 years of follow-up. Consecutive, newly-diagnosed asthmatics ( n =162, age 18–76 years) were randomized for intensive (80 patients) vs . conventional patient education. Effectiveness was evaluated in terms of lung functions, airway hyperresponsiveness (PD 15 ), and quality of life as measured by the generic 15D and disease-specific St. George's Respiratory Questionnaire (SGRQ). Total treatment costs were also estimated. All patients had anti-inflammatory treatment from the beginning. Sixty-four intervention group (IG) patients and 70 control group (CG) patients were evaluated after 5 years. Forced expiratory volume in 1 sec (FEV 1 ) improved only in the IG, and only during the first treatment year. However, PD 15 improved throughout the follow-up. The unscheduled healthcare costs were significantly higher in the CG than in the IG ( P =0·04) and the relative risk for sickness days due to asthma was lower in the IG than in the CG, odds ratio 0·33 (95% CI 0·28; 0·40). However, because there was no significant difference between the groups in any outcome variable or in total costs at 5 years, the incremental cost-effectiveness ratio could not be calculated. The first year intervention had only a short-term beneficial treatment effect, which the CG could catch up during the two last follow-up years, except in FEV 1 . The peak expiratory flow (PEF)-based self-management had no advantage over the symptom-based self-management. However, the intervention had a consistent tendency of being less costly in the long-run. It is possible to conclude tentatively that regular effective medical treatment and control visits during the first treatment year is at least as important for the long-term treatment result as intensive patient education.
Databáze: OpenAIRE