The impact of early intensive glucose control for prophylaxis of complications of type 2 diabetes mellitus (results of UKPDS study and 10-year follow-up study)
| Autor: | E A Ushkalova, Yu Sh Gushchina, Yu. Sh Guschina |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: |
medicine.medical_specialty
vascular complications Physiology Endocrinology Diabetes and Metabolism Population level of glycemia Type 2 diabetes QD415-436 Biochemistry law.invention Endocrinology Randomized controlled trial Quality of life law Internal medicine Diabetes mellitus Internal Medicine medicine QP1-981 education education.field_of_study Nutrition and Dietetics business.industry Public Health Environmental and Occupational Health Type 2 Diabetes Mellitus medicine.disease Surgery Blood pressure diabetes mellitus arterial pressure business Dyslipidemia |
| Zdroj: | Ожирение и метаболизм, Vol 6, Iss 2, Pp 12-18 (2009) |
| ISSN: | 2306-5524 2071-8713 |
| Popis: | At the present time diabetes mellitus (DM) is a main noninfectious disease that not only significantly influences quality of life and life expectancy of every patient but also represents a heavy burden for the healthcare system. Medico social significance of DM is defined by high prevalence of this disease in population and high risk of its specific macro- and microvascular complications. According to latest data the main chain in the development of all specific complications of DM is chronic hyperglycemia, the important role belongs also to arterial hypertension and dyslipidemia. The multicenter randomized controlled study UKPDS assessed the influence of levels of hyperglycemia and arterial pressure as well as common methods of their corrections on development of complications of type 2 DM. The results of the UKPD study showed the significance of the intensive control of blood glucose and arterial pressure for the prophylaxis of type 2 DM complications and lethal outcomes. These observations allowed development of contemporary recommendations for treatment patients with type 2 DM and defined the target levels of HbAlc ( |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|