An investigation of the coagulogical potential of the venoms of some Central Asian snakes

Autor:	H.C. Hemker, L. Ya. Yukel'son, Guido Tans, É. S. Sadykov, N. A. Barabanshchikova, Jan Rosing
Přispěvatelé:	Biochemie
Jazyk:	angličtina
Rok vydání:	1993
Předmět:	chemistry.chemical_classification Viperid venom biology Chemistry Agkistrodon halys Venom Plant Science General Chemistry biology.organism_classification complex mixtures General Biochemistry Genetics and Molecular Biology Enzyme Biochemistry Echis Chemical engineering
Zdroj:	Chemistry of Natural Compounds, 29(3), 384-390. Springer Verlag
ISSN:	0009-3130
DOI:	10.1007/bf00630546
Popis:	The compositions of the proteolytic complexes of the venoms of the crotalid agkistrodon halys halysand the viperid echis multisquamatushave been investigated with the aid of a large number of specific natural and model substrates. A comparative analysis of the results obtained has revealed a predominance in the crotalid venom of fibrinogen-hydrolyzing enzymes, while the viperid venom is characterized as a procoagulant of the prothrombin-activating type. Among the fibrinogenases of the crotalid venom, a thrombin-like enzyme and a plasmin-like proteinase have been revealed and obtained in a purified state. A prothrombin-activating enzyme from the viperid venom has been isolated in the purified state and characterized with the aid of specific substrates.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::471c8dacc26604b057f55d6311007b86 https://doi.org/10.1007/bf00630546 Zobrazit plný text záznamu Full text from SpringerLink