Teriparatide Therapy and Beta-Tricalcium Phosphate Enhance Scaffold Reconstruction of Mouse Femoral Defects

Autor:	Randy N. Rosier, Justin A. Jacobson, Laura Yanoso-Scholl, Edward M. Schwarz, Gino Bradica, Tulin Dadali, Susan V. Bukata, Regis J. O'Keefe, David G. Reynolds, Edward J. Puzas, Michael J. Zuscik, Hani A. Awad
Rok vydání:	2011
Předmět:	Calcium Phosphates Scaffold medicine.medical_treatment Biomedical Engineering Parathyroid hormone Bioengineering Teriparatide therapy Biochemistry Biomaterials Mice Beta-tricalcium phosphate Teriparatide medicine Animals Endocrine system Bone regeneration Saline Mice Inbred BALB C Tissue Scaffolds business.industry Original Articles Combined Modality Therapy Treatment Outcome Bone Substitutes Female Nuclear medicine business Femoral Fractures medicine.drug Biomedical engineering
Zdroj:	Tissue Engineering Part A. 17:389-398
ISSN:	1937-335X 1937-3341
DOI:	10.1089/ten.tea.2010.0115
Popis:	To investigate the efficacy of endocrine parathyroid hormone treatment on tissue-engineered bone regeneration, massive femoral defects in C57Bl/6 mice were reconstructed with either 100:0 or 85:15 poly-lactic acid (PLA)/beta-tricalcium phosphate (β-TCP) scaffolds (hereafter PLA or PLA/βTCP, respectively), which were fabricated with low porosity (
Databáze:	OpenAIRE
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