Sex-related differences in treatment and outcome of chronic limb-threatening ischaemia: a real-world cohort

Autor: Lena Makowski, Jeanette Köppe, Christiane Engelbertz, Leonie Kühnemund, Alicia J Fischer, Stefan A Lange, Patrik Dröge, Thomas Ruhnke, Christian Günster, Nasser Malyar, Joachim Gerß, Eva Freisinger, Holger Reinecke, Jannik Feld
Rok vydání: 2021
Předmět:
Zdroj: European heart journal. 43(18)
ISSN: 1522-9645
Popis: Aims The prevalence of chronic limb-threatening ischaemia (CLTI) is increasing and available data often derive from cohorts with various selection criteria. In the present study, we included CLTI patients and studied sex-related differences in their risk profile, vascular procedures, and long-term outcome. Methods and results We analysed 199 953 unselected patients of the largest public health insurance in Germany (AOK: Local healthcare funds), hospitalized between 2010 and 2017 for a main diagnosis of CLTI. A baseline period of 2 years before index hospitalization to assess comorbidities and previous procedures, and a follow-up period until 2018 were included. Female CLTI patients were older (median 81.4 vs. 73.8 years in males; P Conclusion Female patients with CLTI were older, underwent less often vascular procedures, and received less frequently guideline-recommended medication. Nevertheless, female sex was independently associated with better OS and AFS during follow-up.
Databáze: OpenAIRE