Antibacterial and antifungal activity of methanolic extracts of Salix alba L. against various disease causing pathogens
| Autor: | M Ibrahim, Bilal Javed, K Nawaz, K Malik, H A B Abbas, H M Ahmad, Abdullah Sarwer, H Jawwad, Syeda Sadaf Zehra, F Farooq |
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| Přispěvatelé: | This research received no external funding |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Antifungal Agents
Asergillus terreus salgueiro Salix alba L medicine.disease_cause microfone Medicine and Health Sciences Aspergillus terreus Shigella sonnei MIC Biology (General) Rhizopus stolonifer Salix Antimicrobial Anti-Bacterial Agents Aspergillus Staphylococcus aureus plant extract General Agricultural and Biological Sciences Antibacterial activity Methanolic extracts Rhizopus MBC Streptococcus pyogenes QH301-705.5 Science Microbial Sensitivity Tests Biology Microbiology medicine Escherichia coli A. ornatus Salix alba Plant Extracts Willow Methanol E. coli Botany pathogens S. aureus biology.organism_classification Neisseria gonorrhoeae extrato vegetal QL1-991 QK1-989 antimicrobial Zoology |
| Zdroj: | Brazilian Journal of Biology, Vol 83 (2021) Brazilian Journal of Biology, Volume: 83, Article number: e243332, Published: 29 OCT 2021 Brazilian Journal of Biology v.83 2023 Brazilian Journal of Biology Instituto Internacional de Ecologia (IIE) instacron:IIE Articles |
| ISSN: | 1678-4375 |
| Popis: | The present study was aimed to manifest the antibacterial and antifungal activity of methanolic extracts of Salix alba L. against seven Gram-positive and Gram-negative bacterial pathogens e.g. Streptococcus pyogenes, Staphylococcus aureus (1), S. aureus (2), Shigella sonnei, Escherichia coli (1), E. coli (2) and Neisseria gonorrhoeae and three fungal isolates from the air such as Aspergillus terreus, A. ornatus, and Rhizopus stolonifer. Two different serotypes of S. aureus and E. coli were used. The agar well-diffusion method results showed the dose-dependent response of plant extracts against bacterial and fungal strains while some organisms were found resistant e.g. E. coli (1), S. sonnei, A. terreus and R. stolonifer. The highest antibacterial activity was recorded at 17.000±1.732 mm from 100 mg/mL of leaves methanolic extracts against S. pyogenes while the activity of most of the pathogens decreased after 24 h of incubation. The highest antifungal activity was reported at 11.833±1.0 mm against A. ornatus at 50 mg/mL after 48 h of the incubation period. These experimental findings endorse the use of S. alba in ethnopharmacological formulations and suggest the use of methanolic extracts of the said plant to develop drugs to control the proliferation of resistant disease causing pathogenic microbes. Resumo O presente estudo teve como objetivo manifestar a atividade antibacteriana e antifúngica de extratos metanólicos de Salix alba L. contra sete patógenos bacterianos Gram-positivos e Gram-negativos. Streptococcus pyogenes, Staphylococcus aureus (1), S. aureus (2), Shigella sonnei, Escherichia coli (1), E. coli (2) e Neisseria gonorrhoeae e três isolados de fungos do ar, como Aspergillus terreus, A. ornatus, e Rhizopus stolonifer. Dois sorotipos diferentes de S. aureus e E. coli foram usados. Os resultados do método de difusão em ágar mostraram a resposta dependente da dose de extratos de plantas contra cepas de bactérias e fungos, enquanto alguns organismos foram considerados resistentes, e.g. E. coli (1), S. sonnei, A. terreus e R. stolonifer. A maior atividade antibacteriana foi registrada em 17.000 ± 1.732 de 100 mg/mL de extratos metanólicos de folhas contra S. pyogenes, enquanto a atividade da maioria dos patógenos diminuiu após 24 h de incubação. A maior atividade antifúngica foi relatada em 11,833 ± 1,0 contra A. ornatus a 50 mg/mL após 48 h do período de incubação. Esses achados experimentais endossam o uso de S. alba em formulações etnofarmacológicas e sugerem o uso de extratos metanólicos da referida planta para o desenvolvimento de fármacos que controlem a proliferação de doenças resistentes que causam micróbios patogênicos. |
| Databáze: | OpenAIRE |
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