Effect of Change in Portal Vein Flow Rates on Hepatic Ablations Created with a Bipolar Radiofrequency Ablation Device
| Autor: | Anthony C. Lanctot, Kimberly E. Lind, Gerald D. Dodd |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Portal vein In Vitro Techniques Sensitivity and Specificity 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine medicine Animals Hepatectomy Radiology Nuclear Medicine and imaging Bipolar radiofrequency business.industry Portal Vein Reproducibility of Results Blood flow Equipment Design Portal vein flow Ablation Equipment Failure Analysis Coagulative necrosis Treatment Outcome Liver 030220 oncology & carcinogenesis Catheter Ablation Cattle Female sense organs Radiology business Blood Flow Velocity Liver Circulation |
| Zdroj: | Radiology. 283(2) |
| ISSN: | 1527-1315 |
| Popis: | Purpose To investigate the effect of change in portal vein flow rates on the size and shape of ablations created by a bipolar radiofrequency (RF) ablation device. Materials and Methods This study was exempt from institutional animal care and use committee review. An in vitro bovine liver model perfused with autologous blood via the portal vein at three flow rates (60, 80, 100 mL/min per 100 g of liver) was used. Four ablations, two bipolar and two monopolar (control probe), were made in each of five livers perfused at each flow rate. Short- and long-axis diameters were measured from gross specimens, and volume and sphericity index were calculated for each ablation. A general linear mixed model accounting for correlation within the liver was used to evaluate the effects of flow on ablations. Analyses were performed by using software. Results There was no significant difference in the size or shape of ablations created by the bipolar device at the different flow rates (P.05 for all outcomes). The monopolar device demonstrated the expected inverse association between ablation size and change in flow (P.01 for all outcomes). The mean ± standard deviation of short-axis diameter, long-axis diameter, volume, and sphericity index of the bipolar ablations was 4.3 cm ± 0.1, 4.2 cm ± 0.1, 41.0 cm |
| Databáze: | OpenAIRE |
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