Ultrafast haem–haem electron transfer in cytochrome c oxidase
| Autor: | Audrius Jasaitis, Michael I. Verkhovsky, Mårten Wikström |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Time Factors
electron tunnelling Biophysics Heme 010402 general chemistry Photochemistry 01 natural sciences Redox Biochemistry Electron Transport Electron Transport Complex IV 03 medical and health sciences Electron transfer chemistry.chemical_compound polycyclic compounds Cytochrome c oxidase 030304 developmental biology 0303 health sciences Photolysis protein relaxation biology CO photolysis Chemistry Spectrum Analysis Photodissociation digestive oral and skin physiology Cell Biology Electron transport chain 0104 chemical sciences 3. Good health biology.protein Proton-coupled electron transfer Oxidation-Reduction |
| Zdroj: | Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1506(3):143-146 |
| ISSN: | 0005-2728 |
| DOI: | 10.1016/s0005-2728(01)00220-1 |
| Popis: | Electron transfer between the redox centres is essential for the function of the haem–copper oxidases. To date, the fastest rate of electron transfer between the haem groups has been determined to be ca. 3×105 s−1. Here, we show by optical spectroscopy that about one half of this electron transfer actually occurs at least three orders of magnitude faster, after photolysis of carbon monoxide from the half-reduced bovine heart enzyme. We ascribe this to the true haem–haem electron tunnelling rate between the haem groups. |
| Databáze: | OpenAIRE |
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