Supplementary Figures 1-7 from Unlocking Aspirin's Chemopreventive Activity: Role of Irreversibly Inhibiting Platelet Cyclooxygenase-1

Autor: K. Vinod Vijayan, Elizabeth J. Dial, Subhashree Pradhan, Angela L. Bergeron, Tri Phan, Brian J. Poindexter, Roger J. Bick, Dexing Fang, Lenard M. Lichtenberger
Rok vydání: 2023
Popis: Figure S1. Aspirin and Aspirin-PC does not block the release of TGF from platelets following co-culture with colon cancer cells. Figure S2. Aspirin and Aspirin-PC block platelet induced upregulation of the EMT marker SNAIL in MC-26 cells. Figure S3. Aspirin and Aspirin-PC decrease collagen-induced activation of platelets obtained from the AOM/DSS cancer model. Figure S4. Time course of aspirin (ASA) test drugs on body weight in AOM/DSS mouse colon cancer model. Figure S5. Aspirin and Aspirin-PC do not alter changes in body weight induced by AOM/DSS. Figure S6. Effect of aspirin (ASA) test drugs on fecal hemoglobin in AOM/DSS mouse cancer model. Figure S7. Effect of aspirin (ASA) test drugs on hematocrit in AOM/DSS mouse cancer model.
Databáze: OpenAIRE