Public Health Implications of Rubella Antibody Levels in California
| Autor: | Loring G. Dales, James Chin |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
Male
medicine.medical_specialty Pediatrics Adolescent Antibody level Rubella antibody Antibodies Viral Rubella California Sampling Studies Pregnancy medicine Humans Rubella Vaccine Community Health Services Child biology business.industry Public health Age Factors Public Health Environmental and Occupational Health Infant Articles biochemical phenomena metabolism and nutrition medicine.disease Rubella immunization Immunization Child Preschool biology.protein bacteria Female Immunization history Antibody business |
| Zdroj: | American Journal of Public Health. 72:167-172 |
| ISSN: | 1541-0048 0090-0036 |
| DOI: | 10.2105/ajph.72.2.167 |
| Popis: | Rubella hemaggluttination inhibition (HI) antibody determinations were performed in 1977 on a sample of California school children and in 1977-1979 on young women who were about to be married or who were pregnant. Among the pupils, 66 per cent reported prior rubella immunization; immunization history was more common in younger pupils. Seventy-seven per cent had detectable antibody, with little trend of greater seropositivity at older ages. Over 86 per cent of those with a written record of immunization had detectable antibody. There was no consistent indication of loss of seropositivity with increasing time since immunization. Children immunized at 12-14 months of age tended to have a lower seropositivity rate than those immunized at older ages. Among young women, the prevalence of detectable antibody was 80-83 per cent. Comparison with data obtained in 1968-1969 indicates that rubella immunization has had a marked impact on antibody levels in children but less impact on levels in teenagers and adults. The pool of rubella-susceptibles entering secondary schools will probably not decrease soon, so that rubella outbreaks may continue in high school and college-age populations. Ultimately, school entry immunization requirements should drastically curtail disease activity. In the interim, programs to immunize teenagers and young adult females must be strengthened. (Am J Public Health 1982; 72:167-172.) |
| Databáze: | OpenAIRE |
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