Imbalance of circulating lymphoid cells in Q fever endocarditis
| Autor: | Didier Raoult, Mignane B. Ka, Jean-Louis Mege, Daniel Olive, Eric Ghigo, Françoise Gondois-Rey |
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| Rok vydání: | 2014 |
| Předmět: |
Male
Microbiology (medical) medicine.medical_treatment chemical and pharmacologic phenomena Q fever CD8-Positive T-Lymphocytes Biology Flow cytometry Immune system medicine Humans Immunology and Allergy Endocarditis Lymphocyte Count Aged Aged 80 and over Natural immunosuppression General Immunology and Microbiology medicine.diagnostic_test Immunosuppression Endocarditis Bacterial General Medicine Middle Aged biochemical phenomena metabolism and nutrition medicine.disease Lymphocyte Subsets Killer Cells Natural Q fever endocarditis Blood Infectious Diseases Immunology Female Q Fever CD8 |
| Zdroj: | Pathogens and Disease. 73:1-3 |
| ISSN: | 2049-632X |
| DOI: | 10.1093/femspd/ftu010 |
| Popis: | Q fever endocarditis is characterized by a defective cell-mediated immune response, which may be associated with the dysregulation of circulating subsets of immune cells. In this study, we found that naïve CD8(+) T lymphocytes and CD56dim natural killer cells were decreased patients whereas central memory CD8(+) T lymphocytes were increased. It is likely that these different subsets of immune cells play a role in the immunosuppression accompanying Q fever endocarditis. |
| Databáze: | OpenAIRE |
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