Brain mechanisms of COVID-19-sleep disorders

Autor: Dan Zhu, Jürgen Kurths, Thomas Penzel, Maria Klimova, Oxana Semyachkina-Glushkovskaya, Tingting Yu, Valeria Vinnik, Aysel Mamedova
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Popis: Here, we review findings and trends in sleep research in 2020-2021 demonstrating how COVID-19 and sleep disorders can induce the BBB leakage via neuroinflammation, which might contribute to the 'coronasomnia' phenomenon. The new studies suggest that the controlling of sleep hygiene and quality should be incorporated into the rehabilitation of COVID-19 patients. We also discuss perspective strategies for prevention of COVID-19-related BBB disorders. We demonstrate that sleep might be a novel biomarker of the BBB leakage and the analysis of sleep EEG patterns can be a breakthrough non-invasive technology for diagnosis of the COVID-19-caused BBB disruption.
Databáze: OpenAIRE