New diagnostic modalities and emerging treatments for neonatal bone disease
| Autor: | Stephanie Borg, Nick Bishop |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Bone disease Hypophosphatasia 030209 endocrinology & metabolism Infant Premature Diseases Infant Newborn Diseases Diagnostic modalities 03 medical and health sciences 0302 clinical medicine Rapid access medicine Humans Neonatology Intensive care medicine business.industry Obstetrics and Gynecology Infant Osteogenesis Imperfecta medicine.disease Hyperparathyroidism Primary 030104 developmental biology Myositis Ossificans Pediatrics Perinatology and Child Health Research studies Personalized medicine Bone Diseases business Infant Premature |
| Zdroj: | Early human development. 126 |
| ISSN: | 1872-6232 |
| Popis: | Bone disease in the neonatal period has often been regarded as an issue affecting premature infants, or a collection of rare and ultra-rare disorders that most neonatologists will see only once or twice each year, or possibly each decade. The emergence of targeted therapies for some of these rare disorders means that neonatologists may be faced with diagnostic dilemmas that need a rapid solution in order to access management options that did not previously exist. The diagnostic modalities available to the neonatologist have not changed a great deal in recent years; blood tests and radiographs still form the mainstays with other techniques usually reserved for research studies, but rapid access to genomic testing is emergent. This paper provides an update around diagnosis and management of bone problems likely to present to the neonatologist. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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