Histiocytic sarcoma of the neck: A case report
| Autor: | Jian Zhou, Feng-Lei Xu, Yue Liu, Wanchun Wang |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Cancer Research
Pathology medicine.medical_specialty business.industry CD68 Neck mass Cancer Articles Hyperplasia Histiocytic sarcoma medicine.disease 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Oncology 030220 oncology & carcinogenesis medicine Immunohistochemistry Acute monocytic leukemia Sarcoma medicine.symptom business |
| Zdroj: | Molecular and clinical oncology. 9(1) |
| ISSN: | 2049-9450 |
| Popis: | Histiocytic sarcoma (HS) is a term used to describe malignant hyperplasia of cells exhibiting morphological and immunophenotypical characteristics similar to those of mature cells, with expression of one or more tissue cell markers, excluding acute monocytic leukemia and primitive monocytic sarcoma. We herein describe a case of histiocytic sarcoma of the neck supported by histopathological and immunohistological evidence. A 53-year-old female patient of Chinese descent presented with a rapidly enlarging right neck mass. Imaging studies revealed multiple right cervical lymphadenectases with right jugular vein involvement. The tumor was composed of diffusely distributed large non-cohesive tumor cells, round or oval and focally spindle-shaped. The tumor cells were immunopositive for macrophage-associated antigen CD68 and lysosomes, mostly consistent with a diagnosis of HS. HS is very prone to systemic metastasis; therefore, early diagnosis and timely treatment are crucial. |
| Databáze: | OpenAIRE |
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