Intravenous Ceftriaxone for Syphilitic Uveitis
| Autor: | Rafael de Pinho Queiroz, Danuza O. Machado Azevedo, Wesley Ribeiro Campos, Daniel Vitor Vasconcelos-Santos, Juliana Fulgêncio Henriques, Fernanda A. Agostini |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Adult Complementary Therapies Male medicine.medical_specialty 030106 microbiology Visual Acuity Administration Oral Multimodal Imaging Eye Infections Bacterial Neurosyphilis 03 medical and health sciences Syphilis Serodiagnosis 0302 clinical medicine medicine Immunology and Allergy Humans Syphilis Fluorescein Angiography Infusions Intravenous Glucocorticoids Aged Retrospective Studies medicine.diagnostic_test business.industry Ceftriaxone Chorioretinitis Uveitis Posterior Middle Aged medicine.disease Fluorescein angiography Dermatology Surgery Anti-Bacterial Agents Penicillin Ophthalmology 030221 ophthalmology & optometry business Uveitis Tomography Optical Coherence medicine.drug |
| Zdroj: | Ocular immunology and inflammation. 26(7) |
| ISSN: | 1744-5078 |
| Popis: | Report of clinical/multimodal imaging outcomes of patients with syphilitic uveitis alternatively treated with intravenous(IV) ceftriaxone, due to unavailability of penicillin G.Chart review of all cases of syphilitic uveitis presenting to Hospital São Geraldo/HC-UFMG and treated with intravenous ceftriaxone, between January and August 2014. Clinical, serological and ophthalmological data were collected.Twelve consecutive patients with syphilitic uveitis receiving IV ceftriaxone were identified. All 24 eyes had active intraocular inflammation on clinical examination. All patients received IV ceftriaxone (2-4 g daily) for 14-21 days, supplemented with oral corticosteroid as needed in 9 patients (75%), after documented clinical response. Improvement in intraocular inflammation was seen in all 24 eyes, with median best-corrected visual acuity (BCVA) increasing from 20/50 to 20/20, after a mean follow-up of 5.3 months.IV ceftriaxone may be an effective alternative for treatment of syphilitic uveitis, in the setting of unavailability of penicillin G. |
| Databáze: | OpenAIRE |
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