Deoxymulundocandin--a new echinocandin type antifungal antibiotic
| Autor: | B. N. Ganguli, Kirity Roy, R. G. Bhat, Jurgen Blumbach, S. N. Sawant, Triptikumar Mukhopadhyay, H. Kogler, H. W. Fehlhaber |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Pharmacology
Antifungal Agents biology Echinocandin Stereochemistry Antifungal antibiotic medicine.drug_class Antibiotics Fungi imperfecti Microbial Sensitivity Tests DEPT biology.organism_classification Peptides Cyclic Gas Chromatography-Mass Spectrometry Microbiology Echinocandins Aspergillus Drug Discovery medicine Deoxymulundocandin Aspergillus sydowii Mycelium Chromatography High Pressure Liquid medicine.drug |
| Zdroj: | The Journal of antibiotics. 45(5) |
| ISSN: | 0021-8820 |
| Popis: | A new echinocandin type antifungal antibiotic, deoxymulundocandin, C48H77N7O15, was isolated from the culture filtrate and mycelia of a fungal culture, Aspergillus sydowii (Bainier and Sartory) Thorn and Church var. nov. mulundensis Roy (Culture No. Y-30462). The structure was established by comparative GC-MS analyses of the derivatized acid hydrolysates of deoxymulundocandin and mulundocandin as well as by the high field NMR experiments (COSY, NOESY and DEPT). |
| Databáze: | OpenAIRE |
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