Uncovering the mysteries of hantavirus infections
| Autor: | Satu Mäkelä, Heikki Henttonen, Antti Vaheri, Jussi Hepojoki, Jukka Mustonen, Tarja Sironen, Tomas Strandin |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Orthohantavirus
Transcription Genetic Hantavirus Infections animal diseases viruses Andes virus Rodentia Genome Viral CD8-Positive T-Lymphocytes Vascular leakage Virus Replication Microbiology Capillary Permeability 03 medical and health sciences Immunopathology Animals Humans Hantaan virus 030304 developmental biology Hantavirus 0303 health sciences General Immunology and Microbiology biology 030306 microbiology Endothelial Cells virus diseases Virus Internalization biology.organism_classification Virology respiratory tract diseases 3. Good health Infectious Diseases Viral replication Carrier State Receptors Virus Puumala virus Hantavirus Infection |
| Zdroj: | Nature Reviews Microbiology; Vol 11 |
| ISSN: | 1740-1526 |
| DOI: | 10.1038/nrmicro3066 |
| Popis: | Hantaviruses are negative-sense single-stranded RNA viruses that infect many species of rodents, shrews, moles and bats. Infection in these reservoir hosts is almost asymptomatic, but some rodent-borne hantaviruses also infect humans, causing either haemorrhagic fever with renal syndrome (HFRS) or hantavirus cardiopulmonary syndrome (HCPS). In this Review, we discuss the basic molecular properties and cell biology of hantaviruses and offer an overview of virus-induced pathology, in particular vascular leakage and immunopathology. |
| Databáze: | OpenAIRE |
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