Life-threatening pulmonary hypertension and right ventricular failure complicating calcium and phosphate replacement in the intensive care unit
| Autor: | Timothy Felton, B. A. McCormick, Simon Finfer, M. McD. Fisher |
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| Rok vydání: | 2006 |
| Předmět: |
Adult
Male Critical Care Potassium Compounds Hypertension Pulmonary Ventricular Dysfunction Right medicine.medical_treatment Lung injury Phosphates law.invention Extracorporeal Membrane Oxygenation Postoperative Complications law Intensive care medicine Extracorporeal membrane oxygenation Humans Drug Interactions Adverse effect Heart Failure Septic shock business.industry Respiratory disease medicine.disease Calcium Gluconate Pulmonary hypertension Intensive care unit Anesthesiology and Pain Medicine Anesthesia business |
| Zdroj: | Anaesthesia. 61:49-53 |
| ISSN: | 1365-2044 0003-2409 |
| DOI: | 10.1111/j.1365-2044.2005.04381.x |
| Popis: | A 43-year-old man developed septic shock and acute lung injury after surgery to drain an ischiorectal abscess. In the intensive care unit he initially improved but developed severe hypoxaemia, right ventricular failure and pulmonary hypertension 90 min after receiving intravenous calcium gluconate and potassium phosphate, best explained by the formation of a calcium-phosphate precipitant that resulted in aggregate anaphylaxis. His rapid deterioration and lack of response to conventional therapies necessitated support with extracorporeal membrane oxygenation that was life saving. This adverse event has altered local practice regarding calcium and phosphate replacement and has implications for all intensive care units. |
| Databáze: | OpenAIRE |
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