Serum cotinine and prognosis in breast cancer
| Autor: | M. Doig, O. F. Agbaje, Lorna Johnson, Ian S. Fentiman |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Oncology
Cancer Research medicine.medical_specialty Breast Neoplasms Disease-Free Survival Cohort Studies chemistry.chemical_compound Serum cotinine Breast cancer Risk Factors Nodal status Internal medicine Humans Medicine Cotinine Aged A determinant Early breast cancer business.industry Smoking Middle Aged Prognosis medicine.disease chemistry Tumour size Lymphatic Metastasis Female business Cohort study |
| Zdroj: | Breast Cancer Research and Treatment. 134:811-814 |
| ISSN: | 1573-7217 0167-6806 |
| Popis: | Various studies have suggested that women who smoke have a worse prognosis if they develop breast cancer. Cotinine levels have been measured in sera from 511 patients with stage I and II breast cancer diagnosed between 1975 and 1980, all of whom had complete follow-up. Although the known prognostic factors, axillary nodal status, tumour size and grade were found to be significant, there was no relationship between serum cotinine and metastasis-free survival. A point estimate of serum cotinine was not found to be a determinant of survival in women with early breast cancer. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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