Adjunctive benefits of systemic metronidazole on non-surgical treatment of peri-implantitis. A randomized placebo-controlled clinical trial
| Autor: | Juan Blanco, Alex Pico, Antonio Liñares, Pilar Gándara, Carlota Blanco, Jose Dopico |
|---|---|
| Přispěvatelé: | Universidade de Santiago de Compostela. Departamento de Cirurxía e Especialidades Médico-Cirúrxicas |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Peri-implantitis medicine.drug_class medicine.medical_treatment Antibiotics Placebo Internal medicine Metronidazole medicine Tannerella forsythia Humans Dental Implants Debridement biology business.industry Antibiotic Campylobacter rectus biology.organism_classification Peri-Implantitis Clinical trial Treatment Treatment Outcome Non-surgical Photochemotherapy Periodontics Periodontal Index business medicine.drug |
| Zdroj: | Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela instname |
| Popis: | Aim: To study clinical, radiographic, and microbiological outcomes after non-surgical therapy of peri-implantitis with or without adjunctive systemic metronidazole. Materials and Methods: A randomized placebo-controlled clinical trial was carried out in 32 subjects (62 implants) diagnosed with peri-implantitis. Implants received a mechanical non-surgical debridement session and systemic metronidazole or placebo. Clinical, radiographic, and microbiological outcomes were evaluated at baseline, 3, 6, and 12 months. Results: After 12 months, the test treatment resulted in significantly greater PPD reduction (2.53 vs. 1.02 mm) and CAL gain (2.14 vs. 0.53 mm) (p value |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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