Rapid Detection of Microbial Contamination in Intravenous Fluids by ATP-Based Monitoring System
| Autor: | Hiroyuki Furukawa, Kyoji Kouda, Ryosuke Tsuruta, Hirofumi Yamasaki, Akira Kamiya, Shigeharu Oie |
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| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Adenosine monophosphate 030106 microbiology Microbial contamination Rapid detection Serratia Infections 03 medical and health sciences chemistry.chemical_compound Adenosine Triphosphate 0302 clinical medicine Bacillus cereus Nucleotidases Humans Candida tropicalis 030212 general & internal medicine Infusions Intravenous Serratia marcescens Chromatography Chemistry Candidiasis Monitoring system Bacterial Infections General Medicine Contamination Infectious Diseases Mycoses Fluid Therapy Drug Contamination Adenosine triphosphate |
| Zdroj: | Japanese Journal of Infectious Diseases. 73:363-365 |
| ISSN: | 1884-2836 1344-6304 |
| DOI: | 10.7883/yoken.jjid.2019.534 |
| Popis: | In this study, we investigated four clinical cases of microbial contamination of in-use intravenous infusion fluid, detected by measuring "Adenosine triphosphate (ATP) + adenosine monophosphate (AMP)" ("ATP+AMP") levels. High "ATP+AMP" values correlate with microbial contamination, and by utilizing these values as indicator for microbial contamination possibility, we were able to rapidly detect the contamination and recommend replacement of catheters and administration sets. In three out of four cases, changing the infusion fluid led to improvement in the condition of the patients. "ATP+AMP" levels can be used to confirm microbial contamination of in-use intravenous infusion fluids, as it is fast (several minites) and convenient to measure them. |
| Databáze: | OpenAIRE |
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