Petechial skin rash associated with CoronaVac vaccination: first cutaneous side effect report before phase 3 results
| Autor: | Filiz Cebeci, İlkay Kartal |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Weakness
medicine.medical_specialty Drug-Related Side Effects and Adverse Reactions Side effect business.industry Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Petechial rash Exanthema Administration Cutaneous 030226 pharmacology & pharmacy Rash Dermatology Vaccination 03 medical and health sciences 0302 clinical medicine Immunization Injection site pain medicine Humans 030212 general & internal medicine General Pharmacology Toxicology and Pharmaceutics medicine.symptom business |
| Zdroj: | European Journal of Hospital Pharmacy. 30:e1-e1 |
| ISSN: | 2047-9964 2047-9956 |
| DOI: | 10.1136/ejhpharm-2021-002794 |
| Popis: | Due to the newness of the virus, side effects of vaccines specific to SARS-CoV-2 are not yet known. CoronaVac, a purified inactivated SARS-CoV-2 vaccine developed by Sinovac Biotech (Beijing, China), has been shown to induce SARS-CoV-2-specific neutralising antibodies in mice, rats, non-human primates and in macaques.1 CoronaVac was shown to be well tolerated and did not cause dose-related safety concerns in phase 1 and 2 clinical studies involving healthy individuals aged 18–59 years2 and those aged 60 years and older.3 The most common symptom was injection site pain, and hypersensitivity reactions were the least reported side effects.2 We do not know the phase 3 efficacy and side effect results of CoronaVac, although vaccination has started. Turkey has decided on the CoronaVac within the vaccine market and is currently continuing the vaccination of elderly people following health workers. Here we share up-to-date data on an elderly person who developed post-vaccination side effects in the form of a petechial rash. An 82-year-old woman presented with weakness, burning in the legs and a rash. A diffuse petechial rash was observed on both lower extremities during dermatological examination (figure 1A,B). It was learned that … |
| Databáze: | OpenAIRE |
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