Impact of Left Ventricular Hypertrophy on Peak Serum Troponin T Levels in Patients With Acute Myocardial Infarction
| Autor: | Senthil A. Kumar, Troy Loethen, Joshua Payne, Kevin Boyle, Rugheed Ghadban, Richard W. Madsen, Martin A. Alpert |
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| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty 030204 cardiovascular system & hematology Left ventricular hypertrophy Severity of Illness Index Muscle hypertrophy 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Troponin T Internal medicine Troponin I medicine Humans cardiovascular diseases 030212 general & internal medicine Myocardial infarction Non-ST Elevated Myocardial Infarction Aged Retrospective Studies Creatinine Ejection fraction biology business.industry Middle Aged medicine.disease Troponin chemistry Cardiology biology.protein ST Elevation Myocardial Infarction Female Hypertrophy Left Ventricular Cardiology and Cardiovascular Medicine business |
| Zdroj: | The American Journal of Cardiology. 123:1745-1750 |
| ISSN: | 0002-9149 |
| DOI: | 10.1016/j.amjcard.2019.02.044 |
| Popis: | Previous studies have reported that peak serum troponin I levels were disproportionately elevated in patients with acute anterior ST-segment elevation myocardial infarction (STEMI) and left ventricular (LV) hypertrophy (LVH) compared with those with normal LV mass. The purpose of this retrospective study was to assess the relation of peak serum troponin T levels in patients with normal LV mass and in subjects with mild, moderate, and severe LVH in patients with acute STEMI or non-ST segment elevation myocardial infarction (NSTEMI) when stratified on variables that might be expected to affect serum troponin T levels. The study population consisted of 262 patients; 91 with STEMI and 161 with NSTEMI. Serum troponin levels and 2-dimensional echocardiograms were obtained within the first 24 hours of hospitalization for STEMI or NSTEMI. There was no significant difference in serum troponin T levels in LV mass and/or LVH groups (p = 0.3210). There was no significant difference in serum troponin T levels in LV mass and/or LVH groups when these data were stratified on third variables including serum creatinine1.2 mg/dl (p = 0.3681), LV ejection fraction60% (p = 0.0978), STEMI (p = 0.2576), NSTEMI (p = 0.4994), and location of severe coronary stenosis (p = 0.1981). The results of this study suggest that there is no association between peak serum troponin T levels and LV mass and/or LVH groups when such groups are stratified on a third variable that may influence peak serum troponin T levels. |
| Databáze: | OpenAIRE |
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