Autoimmune Myasthenia Gravis in Childhood
Autor: | P. Ian Andrews |
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Rok vydání: | 2004 |
Předmět: |
Diagnostic methods
medicine.medical_treatment Neuromuscular Junction Diagnostic accuracy Adjuvants Immunologic Autoimmune Process immune system diseases Myasthenia Gravis Humans Medicine Receptors Cholinergic Child Muscle Skeletal Autoantibodies business.industry Age Factors Musk antibody Receptor Protein-Tyrosine Kinases medicine.disease Myasthenia gravis nervous system diseases Thymectomy Neurology Immunology Cholinesterase Inhibitors Neurology (clinical) business |
Zdroj: | Seminars in Neurology. 24:101-110 |
ISSN: | 1098-9021 0271-8235 |
DOI: | 10.1055/s-2004-829591 |
Popis: | The recent identification of an autoimmune process targeting muscle-specific kinase (MuSK) in a subset of seronegative patients with autoimmune myasthenia gravis promises to improve diagnostic accuracy and redirect therapy in at least some seronegative children and adolescents with myasthenia. Clinical features, diagnostic methods, and management strategies pertinent to children with autoimmune myasthenia are discussed, as well as the emerging data regarding the anti-MuSK autoimmune process in myasthenia gravis. |
Databáze: | OpenAIRE |
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